SSM3 (tetraTFA)
SSM3 tetraTFA is a potent synthetic furin inhibitor with an EC50 and a Ki of 54 nM and 12 nM, respectively. SSM3 tetraTFA is able to block furin-dependent cell surface processing of anthrax protective antigen-83 in vitro[1][2].
Product Specifications
CAS Number
2320930-10-5
UNSPSC
12352005
Target
Furin
Related Pathways
Metabolic Enzyme/Protease
Applications
COVID-19-immunoregulation
Field of Research
Infection
Solubility
10 mM in DMSO
Smiles
N=C(N)NC(C=C1)=CC=C1O[C@@H]2[C@H](C[C@@H](NC(N)=N)[C@H](OC3=CC=C(NC(N)=N)C=C3)C2)NC(N)=N.OC(C(F)(F)F)=O.OC(C(F)(F)F)=O.OC(C(F)(F)F)=O.OC(C(F)(F)F)=O
Molecular Formula
C30H36F12N12O10
Molecular Weight
952.66
References & Citations
[1]Albert G Remacle, et al. Selective and Potent Furin Inhibitors Protect Cells From Anthrax Without Significant Toxicity. Int J Biochem Cell Biol|[2]Guan-Sheng Jiao, et al. Synthetic Small Molecule Furin Inhibitors Derived From 2,5-dideoxystreptamine. Proc Natl Acad Sci U S A. 2006 Dec 26;103 (52) :19707-12.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Frequently Asked Questions
More Discoveries
Explore Other Products
Browse additional items from our catalog
T3300-12-ML405 100 µL
TSPAN12, CT (Tetraspanin-12, Tspan-12, Transmembrane 4 Superfamily Member 12, Tetraspan NET-2, NET2, TM4SF12, UNQ774/PRO1568) (MaxLight 405) discontinued
Sign In for Pricing
View Details 
NBP3-06474-50ul 50 µL
Mouse Monoclonal Influenza A H6N1 Hemagglutinin Antibody (8A10D8)
Sign In for Pricing
View Details 
E4A11A59-7-M-100 100 µg
Human anti-Salmonella enteritidis ribosome protein L7 IgM
Sign In for Pricing
View Details 
BNC042745-100 1x 100 µL
PD-L1 / PDCD1LG1 / CD274 / B7-H1 (Cancer Immunotherapy Target) (PDL1/2745), CF405S conjugate, 0.1mg/mL
Sign In for Pricing
View Details