Masoprocol (Standard)

Masoprocol (Standard) is the analytical standard of Masoprocol. This product is intended for research and analytical applications. Masoprocol (meso-Nordihydroguaiaretic acid) is a potent and orally active lipoxygenase inhibitor. Masoprocol shows antihyperglycemic activity. Masoprocol decreases the glucose concentration and hepatic triglyceride in vivo. Masoprocol has the potential for the research of type II diabetes[1][2][3].

Product Specifications

CAS Number

[27686-84-6]

UNSPSC

12352100

Target

Lipoxygenase; Reference Standards

Related Pathways

Metabolic Enzyme/Protease; Others

Field of Research

Metabolic Disease; Cancer

Smiles

OC(C=C1C[C@@H](C)[C@@H](C)CC2=CC(O)=C(C=C2)O)=C(C=C1)O

Molecular Formula

C18H22O4

Molecular Weight

302.36

References & Citations

[1]Luo J, et al. Masoprocol (nordihydroguaiaretic acid) : a new antihyperglycemic agent isolated from the creosote bush (Larrea tridentata) . Eur J Pharmacol. 1998 Apr 3;346 (1) :77-9.|[2]Reed MJ, et al. Effect of masoprocol on carbohydrate and lipid metabolism in a rat model of Type II diabetes. Diabetologia. 1999 Jan;42 (1) :102-6.|[3]Scribner KA, et al. Masoprocol decreases serum triglyceride concentrations in rats with fructose-induced hypertriglyceridemia. Metabolism. 2000 Sep;49 (9) :1106-10.