Pravibismane

Pravibismane (BisEDT; MBN-101) is a broad-spectrum topical anti-infective and anti-biofilm agent. Pravibismane disrupts bacterial bioenergetics by reducing bacterial concentrations of ATP in both planktonic and biofilm phenotypes and exhibits potent anti-biofilm activity against diabetic foot infections (DFI) -relevant pathogens, such as S. aureus and P. aeruginosa. Pravibismane can be used for the study of diabetic foot infections[1].

Product Specifications

CAS Number

175880-68-9

Product Name Alternative

BisEDT; MBN-101

UNSPSC

12352005

Target

Bacterial

Related Pathways

Anti-infection

Applications

COVID-19-immunoregulation

Field of Research

Infection

Smiles

[Bi]1(SCCS1)SCCS[Bi]2SCCS2

Molecular Formula

C6H12Bi2S6

Molecular Weight

694.51

References & Citations

[1]Lipsky BA, et al. Topical pravibismane as adjunctive therapy for moderate or severe diabetic foot infections: A phase 1b randomized, multicenter, double-blind, placebo-controlled trial. Int Wound J. 2024 Apr;21 (4) :e14817.