Danicamtiv-d3
Danicamtiv-d3 (MYK-491-d3) is a deuterated labeled Danicamtiv. Danicamtiv (MYK-491), an inotropic agent, is a selective allosteric activator of cardiac myosin. Danicamtiv increases cardiac systolic function and preserves mechanical efficiency[1].
Product Specifications
CAS Number
2925925-82-0
Product Name Alternative
MYK-491-d3
UNSPSC
12352005
Target
Isotope-Labeled Compounds; Myosin
Related Pathways
Cytoskeleton; Others
Applications
Neuroscience-Neuromodulation
Field of Research
Cardiovascular Disease
Smiles
O=S([C@@](C1CCN(CC1)C(NC2=NOC=C2)=O)(C)F)(C3=CN(N=C3C(F)F)C([2H])([2H])[2H])=O
Molecular Formula
C16H17D3F3N5O4S
Molecular Weight
438.44
References & Citations
[1]Sarah Fernandes, et al. Abstract 15707: MYK-491, a Novel Small-Molecule Cardiac Myosin Activator Increases Cardiac Systolic Function and Preserves Mechanical Efficiency: Pre-Clinical in vivo and in vitro Evidence. Circulation. 2019;140:A15707.
Shipping Conditions
Room temperature
Scientific Category
Isotope-Labeled Compounds
Clinical Information
No Development Reported
Frequently Asked Questions
More Discoveries
Explore Other Products
Browse additional items from our catalog
RC227906 10 µg
KIAA1712 (CEP44) (NM_001145314) Human Tagged ORF Clone
Sign In for Pricing
View Details 035143-PE 200 µL
ERAS, NT (F66) (ERAS, HRAS2, HRASP, GTPase ERas, Embryonic stem cell-expressed Ras) (PE) discontinued
Sign In for Pricing
View Details 
138287-APC 100 µL
RHAG (Ammonium Transporter Rh Type A, Erythrocyte Membrane Glycoprotein Rh50, Erythrocyte Plasma Membrane 50kD Glycoprotein, Rh50A, Rhesus Blood Group Family Type A Glycoprotein, Rh Family Type A Glycoprotein, Rh Type A Glycoprotein, Rhesus Blood Group-associated Ammonia Channel, Rhesus Blood Group-associated Glycoprotein, CD241, RH50) (APC)
Sign In for Pricing
View Details 
TL501311V 500 µL Each
Mbd1 Mouse shRNA Lentiviral Particle (Locus ID 17190)
Sign In for Pricing
View Details