Danicamtiv-d6
Danicamtiv-d6 (MYK-491-d6) is a deuterated labeled Danicamtiv. Danicamtiv (MYK-491), an inotropic agent, is a selective allosteric activator of cardiac myosin. Danicamtiv increases cardiac systolic function and preserves mechanical efficiency[1].
Product Specifications
CAS Number
1970975-54-2
Product Name Alternative
MYK-491-d6
UNSPSC
12352005
Target
Isotope-Labeled Compounds; Myosin
Related Pathways
Cytoskeleton; Others
Field of Research
Cardiovascular Disease
Smiles
O=S([C@@](C1CCN(CC1)C(NC2=NOC=C2)=O)(C([2H])([2H])[2H])F)(C3=CN(N=C3C(F)F)C([2H])([2H])[2H])=O
Molecular Formula
C16H14D6F3N5O4S
Molecular Weight
441.46
References & Citations
[1]Sarah Fernandes, et al. Abstract 15707: MYK-491, a Novel Small-Molecule Cardiac Myosin Activator Increases Cardiac Systolic Function and Preserves Mechanical Efficiency: Pre-Clinical in vivo and in vitro Evidence. Circulation. 2019;140:A15707.
Shipping Conditions
Room temperature
Scientific Category
Isotope-Labeled Compounds
Clinical Information
No Development Reported
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