Cedazuridine (Standard)

Cedazuridine (Standard) is the analytical standard of Cedazuridine. This product is intended for research and analytical applications. Cedazuridine (E7727) (Compound 7a) is an orally active cytidine deaminase (CDA) inhibitor with an IC50 value of 0.4 μM. Cedazuridine can be used for cancer research[1].

Product Specifications

CAS Number

[1141397-80-9]

UNSPSC

12352100

Target

Others; Reference Standards

Related Pathways

Others

Field of Research

Cancer

Smiles

O[C@H]1C(F)(F)[C@H](N(CC[C@@H](O)N2)C2=O)O[C@@H]1CO

Molecular Formula

C9H14F2N2O5

Molecular Weight

268.21

References & Citations

[1]Ferraris D, et al. Design, synthesis, and pharmacological evaluation of fluorinated tetrahydrouridine derivatives as inhibitors of cytidine deaminase. J Med Chem. 2014 Mar 27; 57 (6) :2582-8.|[2]Ramsey H E, et al. Oral azacitidine and cedazuridine approximate parenteral azacitidine efficacy in murine model. Targeted Oncology, 2020, 15 (2) : 231-240.