Ceclazepide
Ceclazepide (TR2-A), a CCK2R antagonist, is an orally active Mycobacterium abscessus inhibitor. Ceclazepide inhibits acid secretion in rats. Ceclazepide effectively suppresses the growth of M. abscessus wild-type strain and multiple subspecies. Ceclazepide inhibits M. abscessus growth within macrophages without causing harm[1][2].
Product Specifications
CAS Number
1801749-44-9
Product Name Alternative
TR2-A
UNSPSC
12352005
Target
Bacterial; Cholecystokinin Receptor
Related Pathways
Anti-infection; GPCR/G Protein; Neuronal Signaling
Field of Research
Infection; Cardiovascular Disease
Smiles
CC(OCC(C)(C)C(CN1C2=CC=CC=C2C(C3=CC=CC=N3)=N[C@H](C1=O)NC(NC4=CC(NC)=CC=C4)=O)=O)=O
Molecular Formula
C30H32N6O5
Molecular Weight
556.61
References & Citations
[1]K.L. Therese, et al. Ceclazepide as novel Mycobacterium abscessus inhibitor. bioRxiv. April 03, 2024.|[2]Chen D, et al. Neuroendocrine mechanism of gastric acid secretion: Historical perspectives and recent developments in physiology and pharmacology. J Neuroendocrinol. 2023 Nov;35 (11) :e13305.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Frequently Asked Questions
More Discoveries
Explore Other Products
Browse additional items from our catalog
MBS7152467 Inquire
Rabbit anti-Dictyoglomus thermophilum (strain 35947/DSM 3960/H-6-12) amyC Polyclonal Antibody
Sign In for Pricing
View Details 