Crisnatol (Standard)

Crisnatol (Standard) is the analytical standard of Crisnatol. This product is intended for research and analytical applications. Crisnatol (BWA770U) is an orally active and anticancer agent, and a member of the arylmethylaminopropanediol class of DNA intercalators. Crisnatol shows in vitro cytotoxicity against human breast cancer cells, but not normal human skin fibroblasts[1][2][3].

Product Specifications

CAS Number

[96389-68-3]

UNSPSC

12352100

Target

DNA/RNA Synthesis; Reference Standards

Related Pathways

Cell Cycle/DNA Damage; Others

Field of Research

Cancer

Smiles

OCC(C)(NCC1=C2C=CC=CC2=C3C(C4=CC=CC=C4C=C3)=C1)CO

Molecular Formula

C23H23NO2

Molecular Weight

345.43

References & Citations

[1]Adams DJ. In vitro pharmacodynamic assay for cancer drug development: application to crisnatol, a new DNA intercalator. Cancer Res. 1989 Dec 1;49 (23) :6615-20. |[2]Patel DK, et al. Metabolism of a novel antitumor agent, crisnatol, by a human hepatoma cell line, Hep G2, and hepatic microsomes. Characterization of metabolites. Biochem Pharmacol. 1991 Jul 5;42 (2) :337-46. |[3]Patel DK, et al. Disposition, metabolism, and excretion of the anticancer agent crisnatol in the rat. Drug Metab Dispos. 1991 Mar-Apr;19 (2) :491-7.