Ifoxetine
Ifoxetine (CGP 15210G) is an inhibitor of 5-HT reuptake. Ifoxetine specifically and selectively blocks the 5-HT reuptake in the brain without affecting the 5-HT uptake processes in the periphery (blood platelets) . Ifoxetine inhibits the uptake of radiolabelled 5-HT into rat brain synaptosomes in vitro or ex vivo. Ifoxetine has antidepressant properties[1][2].
Product Specifications
CAS Number
66208-11-5
Product Name Alternative
CGP-15210G
UNSPSC
12352005
Target
5-HT Receptor
Related Pathways
GPCR/G Protein; Neuronal Signaling
Field of Research
Neurological Disease
Smiles
CC(C(C)=CC=C1)=C1O[C@H]2[C@H](CNCC2)O
Molecular Formula
C13H19NO2
Molecular Weight
221.30
References & Citations
[1]P. C. Waldmeier, et al. Ifoxetine: An Unusual 5-HT Uptake Inhibitor or an Inhibitor of 5-HT Release? Pharmacopsychiatry 1986; 19 (4) : 318-319.|[2]Delini-Stula A, et al. First clinical experience with ifoxetine, a new 5-HT reuptake blocker with particular emphasis on the side-effect profile of the 5-HT-uptake inhibiting drugs. Int Clin Psychopharmacol. 1987 Jul;2 (3) :201-15.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Frequently Asked Questions
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