URB-597 (Standard)
URB-597 (Standard) is the analytical standard of URB-597. This product is intended for research and analytical applications. URB-597 (KDS-4103) is an orally bioavailable and selective FAAH inhibitor. URB-597 inhibits FAAH activity with an IC50s of approximately 5 nM in rat brain membranes, 0.5 nM in intact rat neurons, 3 nM in human liver microsomes. Antidepressant-like effects. Analgesic activity[1].
Product Specifications
CAS Number
[546141-08-6]
UNSPSC
12352100
Target
Autophagy; FAAH; Mitophagy; Reference Standards
Related Pathways
Autophagy; Metabolic Enzyme/Protease; Neuronal Signaling; Others
Field of Research
Neurological Disease
Smiles
O=C(OC1=CC(C2=CC=CC(C(N)=O)=C2)=CC=C1)NC3CCCCC3
Molecular Formula
C20H22N2O3
Molecular Weight
338.40
References & Citations
[1]Daniele Piomelli, et al. Pharmacological profile of the selective FAAH inhibitor KDS-4103 (URB597) . CNS Drug Rev. Spring 2006;12 (1) :21-38.
Shipping Conditions
Room temperature
Scientific Category
Reference Standards
Available Sizes
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