Welcome to GenPrice! Check out our latest updates.

Shopping Cart (0)

Your cart is empty

Add some products to get started!

DCP-LA (Standard)

DCP-LA (Standard) is the analytical standard of DCP-LA. This product is intended for research and analytical applications. DCP-LA (FR236924), a linoleic acid derivative, selectively and directly activates PKCε. DCP-LA activates Ca (2+) /calmodulin-dependent protein kinase II (CaMKII) and inhibits protein phosphatase-1 (PP-1) to stimulate AMPA receptor exocytosis. DCP-LA inhibits activation of caspase-3/-9 and protects neurons at least in part from oxidative stress-induced apoptosis[1][2][3].

Product Specifications

CAS Number

28399-31-7

Product Name Alternative

FR236924 (Standard)

UNSPSC

12352211

Target

Apoptosis; CaMK; Phosphatase; PKC; Reference Standards

Related Pathways

Apoptosis; Epigenetics; Metabolic Enzyme/Protease; Neuronal Signaling; Others; TGF-beta/Smad

Field of Research

Neurological Disease

Smiles

O=C(O)CCCCCCCC1C(CC2C(CCCCC)C2)C1

Molecular Formula

C20H36O2

Molecular Weight

308.50

References & Citations

[1]Kanno T, et al. DCP-LA Activates Cytosolic PKCε by Interacting with the Phosphatidylserine Binding/Associating Sites Arg50 and Ile89 in the C2-Like Domain. Cell Physiol Biochem. 2015;37 (1) :193-200.|[2]Kanno T, et al. DCP-LA stimulates AMPA receptor exocytosis through CaMKII activation due to PP-1 inhibition. J Cell Physiol. 2009 Oct;221 (1) :183-8. |[3]Yaguchi T, et al. Linoleic acid derivative DCP-LA protects neurons from oxidative stress-induced apoptosis by inhibiting caspase-3/-9 activation. Neurochem Res. 2010 May;35 (5) :712-7.

Shipping Conditions

Room temperature

Scientific Category

Reference Standards

Available Sizes

Frequently Asked Questions

More Discoveries

Explore Other Products

Browse additional items from our catalog

Recombinant Rhesus Macaque MORC4 Protein, His (Fc)-Avi-tagged
MORC4-2625R 50 µg

Recombinant Rhesus Macaque MORC4 Protein, His (Fc)-Avi-tagged

Sign In for Pricing
View Details
PRODH2 Antibody
GWB-27C41F 0.05 mg

PRODH2 Antibody

Sign In for Pricing
View Details
AGL 293 Cell Lysate
410167 0.1 mg

AGL 293 Cell Lysate

Sign In for Pricing
View Details
Sheath Fluid 30x
TBS5070-30L 1 L

Sheath Fluid 30x

Sign In for Pricing
View Details
hsa-miR-5787 Primers
MPH03328 150 µL - 10 µM

hsa-miR-5787 Primers

Sign In for Pricing
View Details
Rabbit Polyclonal Acetyl-CoA Carboxylase alpha/ACACA Antibody
NB100-55247 100 µL

Rabbit Polyclonal Acetyl-CoA Carboxylase alpha/ACACA Antibody

Sign In for Pricing
View Details