9-Phenanthrol (Standard)
9-Phenanthrol (Standard) is the analytical standard of 9-Phenanthrol. This product is intended for research and analytical applications. 9-Phenanthrol (9-Hydroxyphenanthrene) is a selective TRPM4 inhibitor with an IC50 of 17 μM. 9-Phenanthrol has no inhibitory activity on TRPM5, TRPC6, and CFTR. 9-Phenanthrol can be used for the research of ischemia-reperfusion injury[1][2].
Product Specifications
UNSPSC
12352100
Target
Reference Standards; TRP Channel
Related Pathways
Membrane Transporter/Ion Channel; Neuronal Signaling; Others
Field of Research
Cardiovascular Disease
Smiles
OC1=CC2=CC=CC=C2C3=CC=CC=C13
Molecular Formula
C14H10O
Molecular Weight
194.23
References & Citations
[1]Wang J, et, al. 9-Phenanthrol, a TRPM4 inhibitor, protects isolated rat hearts from ischemia-reperfusion injury. PLoS One. 2013 Jul 25;8 (7) :e70587. |[2]Guinamard R, et al. The TRPM4 channel inhibitor 9-phenanthrol. Br J Pharmacol. 2014 Apr;171 (7) :1600-13.
Shipping Conditions
Room temperature
Product MSDS
http://file.medchemexpress.com/batch_PDF/HY-108457R/
Scientific Category
Reference Standards
CAS Number
[484-17-3]
Available Sizes
Curated Selection
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