Acoltremon-d3
Acoltremon-d3 (WS-12-d3) is the deuterium labeled Acoltremon. Acoltremon is a potent and selective TRPM8 agonist, the menthol derivative, as a cooling agent. Acoltremon shows analgesic effect, and can be used in chronic neuropathic pain research[1][2].
Product Specifications
Product Name Alternative
WS-12-d3; AR-15512-d3; AVX-012-d3
UNSPSC
12352005
Target
Isotope-Labeled Compounds; TRP Channel
Related Pathways
Membrane Transporter/Ion Channel; Neuronal Signaling; Others
Applications
Neuroscience-Neuromodulation
Field of Research
Neurological Disease
Purity
99.58
Solubility
DMSO : 16.67 mg/mL (ultrasonic)
Smiles
O=C([C@@H]1C[C@@H](CC[C@H]1C(C)C)C)NC(C=C2)=CC=C2OC([2H])([2H])[2H]
Molecular Formula
C18H24D3NO2
Molecular Weight
292.43
References & Citations
[1]Beck B, et al. Prospects for prostate cancer imaging and therapy using high-affinity TRPM8 activators. Cell Calcium. 2007 Mar;41 (3) :285-94. |[2]Ma S, et al. Menthol derivative WS-12 selectively activates transient receptor potential melastatin-8 (TRPM8) ion channels. Pak J Pharm Sci. 2008 Oct;21 (4) :370-8.
Shipping Conditions
Blue Ice
Storage Conditions
-20°C, 3 years (Powder)
Scientific Category
Isotope-Labeled Compounds
Clinical Information
No Development Reported
Available Sizes
Frequently Asked Questions
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