LCI765
LCI765 is an orally active and selective PPARδ agonist, with an EC50 of 0.07 nM. LCI765 can be used for the research of diseases related to energy homeostasis such as metabolic syndrome[1].
Product Specifications
CAS Number
870194-96-0
UNSPSC
12352005
Target
PPAR
Related Pathways
Cell Cycle/DNA Damage; Metabolic Enzyme/Protease; Vitamin D Related/Nuclear Receptor
Field of Research
Metabolic Disease
Smiles
OC(CC1=CC=CC(C2=NOC(C3=CC=CC=C3)=C2C(NCCOC4=CC=C(Cl)C=C4Cl)=O)=C1)=O
Molecular Formula
C26H20Cl2N2O5
Molecular Weight
511.35
References & Citations
[1]Epple R, et al. 3,4,5-Trisubstituted isoxazoles as novel PPARdelta agonists. Part 2. Bioorg Med Chem Lett. 2006 Nov 1;16 (21) :5488-92.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Isoform
PPARγ
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