(R) -Equol (Standard)

(R) -Equol (Standard) is the analytical standard of (R) -Equol. This product is intended for research and analytical applications. (R) -Equol is an agonist of both ERα and ERβ with Kis of 27.4 and 15.4 nM, respectively.

Product Specifications

CAS Number

[221054-79-1]

UNSPSC

12352100

Target

Estrogen Receptor/ERR; Reference Standards

Related Pathways

Others; Vitamin D Related/Nuclear Receptor

Field of Research

Cancer

Smiles

OC1=CC=C2C[C@H](C3=CC=C(O)C=C3)COC2=C1

Molecular Formula

C15H14O3

Molecular Weight

242.27

References & Citations

[1]Setchell KD, et al. S-equol, a potent ligand for estrogen receptor beta, is the exclusive enantiomeric form of the soy isoflavone metabolite produced by human intestinal bacterial flora. Am J Clin Nutr. 2005 May;81 (5) :1072-9.|[2]Magee PJ, et al. Daidzein, R- (+) equol and S- (-) equol inhibit the invasion of MDA-MB-231 breast cancer cells potentially via the down-regulation of matrix metalloproteinase-2. Eur J Nutr. 2014 Feb;53 (1) :345-50.|[3]Brown NM, et al. The chemopreventive action of equol enantiomers in a chemically induced animal model of breast cancer. Carcinogenesis. 2010 May;31 (5) :886-93.