6-Diazo-5-oxo-L-nor-Leucine (Standard)
6-Diazo-5-oxo-L-nor-Leucine (Standard) is the analytical standard of 6-Diazo-5-oxo-L-nor-Leucine. This product is intended for research and analytical applications. 6-Diazo-5-oxo-L-nor-Leucine (L-6-Diazo-5-oxonorleucine; DON) is a glutamine antagonist that irreversibly inhibits the catabolic effect of glutamine. 6-Diazo-5-oxo-L-nor-Leucine shows good anticancer activity (especially in pancreatic cancer) and reduces the self-renewal potential and metastatic capacity of tumour cells. 6-Diazo-5-oxo-L-nor-Leucine also possesses antibacterial and antiviral activity[1][2][3].
Product Specifications
CAS Number
157-03-9
Product Name Alternative
L-6-Diazo-5-oxonorleucine (Standard) ; DON (Standard)
UNSPSC
12352211
Hazard Statement
H301-H311-H331
Target
Antibiotic; Bacterial; Glutaminase; Influenza Virus; Reference Standards
Related Pathways
Anti-infection; Metabolic Enzyme/Protease; Others
Field of Research
Cancer; Infection
Smiles
N[C@@H](CCC(C=[N+]=[N-])=O)C(O)=O
Molecular Formula
C6H9N3O3
Molecular Weight
171.15
Precautions
P261-P264-P270-P271-P280-P302+P352-P304+P340-P330-P361+P364-P403+P233-P405-P501
References & Citations
Shipping Conditions
Room temperature
Scientific Category
Reference Standards
Available Sizes
Frequently Asked Questions
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