Welcome to GenPrice! Check out our latest updates.

Shopping Cart (0)

Your cart is empty

Add some products to get started!

PF-05139962

PF-05139962 is a cyclic sulfone mTOR kinase inhibitor. PF-05139962 exhibits potent mTOR (Ki = 5 nM, pS473 IC50 = 48 nM, pS6 IC50 = 6 nM) inhibitory activity and high selectivity[1].

Product Specifications

CAS Number

1393712-18-9

UNSPSC

12352005

Target

MTOR

Related Pathways

PI3K/Akt/mTOR

Field of Research

Cancer

Smiles

O=C(NCC)NC1=CC=C(C2=NC(N3[C@@H](C)COCC3)=C(CS4(=O)=O)C(CC4)=N2)C=C1

Molecular Formula

C21H27N5O4S

Molecular Weight

445.54

References & Citations

[1] Liu KK, et al. Conformationally-restricted cyclic sulfones as potent and selective mTOR kinase inhibitors. Bioorg Med Chem Lett. 2012 Aug 1;22 (15) :5114-7.

Shipping Conditions

Room temperature

Scientific Category

Reference compound1

Clinical Information

No Development Reported

Frequently Asked Questions

More Discoveries

Explore Other Products

Browse additional items from our catalog

Clcn1 Rabbit Polyclonal Antibody
TA363181 100 µL

Clcn1 Rabbit Polyclonal Antibody

Sign In for Pricing
View Details
Estr-5(10)-ene-3,17-dione
TRC-E888955-25G 25 g

Estr-5(10)-ene-3,17-dione

Sign In for Pricing
View Details
MMP9 (rMMP9/1769), 1mg/mL
BNUM2176-50 1x 50 µL

MMP9 (rMMP9/1769), 1mg/mL

Sign In for Pricing
View Details
FUBP1 Mouse Monoclonal Antibody [Clone ID: AT14F5]
AM50629PU-S 50 µL

FUBP1 Mouse Monoclonal Antibody [Clone ID: AT14F5]

Sign In for Pricing
View Details
CD3E Mouse Monoclonal Antibody [Clone ID: CA-3]
AM20601PU-N 100 µg

CD3E Mouse Monoclonal Antibody [Clone ID: CA-3]

Sign In for Pricing
View Details
Tissue FFPE Sections, Thyroid gland
CS802497 5x 5 µm

Tissue FFPE Sections, Thyroid gland

Sign In for Pricing
View Details