SC-57461
SC-57461 is a potent, selective, and orally effective LTA4 hydrolase (Ki = 23 nM and 27 nM) inhibitor. SC-57461 can significantly inhibit edema. SC-57461 is commonly used in the study of inflammatory skin conditions[1].
Product Specifications
CAS Number
179022-08-3
UNSPSC
12352005
Target
Aminopeptidase
Related Pathways
Metabolic Enzyme/Protease
Field of Research
Inflammation/Immunology
Smiles
O=C(CCN(CCCOC1=CC=C(CC2=CC=CC=C2)C=C1)C)O
Molecular Formula
C20H25NO3
Molecular Weight
327.42
References & Citations
[1]Kachur J F, et al. Pharmacological Characterization of SC-57461A (3-[Methyl [3-[4- (phenylmethyl) phenoxy] propyl] amino] propanoic Acid HCl), a Potent and Selective Inhibitor of Leukotriene A4Hydrolase II: In Vivo Studies[J]. The Journal of pharmacology and experimental therapeutics, 2002, 300 (2) : 583-587.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Frequently Asked Questions
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