SC-57461

SC-57461 is a potent, selective, and orally effective LTA4 hydrolase (Ki = 23 nM and 27 nM) inhibitor. SC-57461 can significantly inhibit edema. SC-57461 is commonly used in the study of inflammatory skin conditions[1].

Product Specifications

CAS Number

[179022-08-3]

UNSPSC

12352005

Target

Aminopeptidase

Related Pathways

Metabolic Enzyme/Protease

Field of Research

Inflammation/Immunology

Smiles

O=C(CCN(CCCOC1=CC=C(CC2=CC=CC=C2)C=C1)C)O

Molecular Formula

C20H25NO3

Molecular Weight

327.42

References & Citations

[1]Kachur J F, et al. Pharmacological Characterization of SC-57461A (3-[Methyl [3-[4- (phenylmethyl) phenoxy] propyl] amino] propanoic Acid HCl), a Potent and Selective Inhibitor of Leukotriene A4Hydrolase II: In Vivo Studies[J]. The Journal of pharmacology and experimental therapeutics, 2002, 300 (2) : 583-587.