Bisindolylmaleimide IV (Standard)
Bisindolylmaleimide IV (Standard) is the analytical standard of Bisindolylmaleimide IV. This product is intended for research and analytical applications. Bisindolylmaleimide IV (Arcyriarubin A) is a potent protein kinase C (PKC) inhibitor, with IC50s ranging from 0.1 to 0.55 μM. Bisindolylmaleimide IV also inhibits PKA (IC50=3.1-11.8μM) [1]. Bisindolylmaleimide IV is a potent, selective inhibitor of human cytomegalovirus (HCMV) replication in cell culture with an IC50 of 0.2 μM[2].
Product Specifications
CAS Number
119139-23-0
UNSPSC
12352100
Target
CMV; PKC; Reference Standards
Related Pathways
Anti-infection; Epigenetics; Others; TGF-beta/Smad
Field of Research
Infection
Smiles
O=C(C(C1=CNC2=C1C=CC=C2)=C3C4=CNC5=C4C=CC=C5)NC3=O
Molecular Formula
C20H13N3O2
Molecular Weight
327.34
References & Citations
[1]Slater MJ, et al. Indolocarbazoles: potent, selective inhibitors of human cytomegalovirus replication. Bioorg Med Chem. 1999 Jun;7 (6) :1067-74.|[2]Davis PD, et al. Inhibitors of protein kinase C. 1. 2,3-Bisarylmaleimides. J Med Chem. 1992 Jan;35 (1) :177-84.
Shipping Conditions
Room temperature
Scientific Category
Reference Standards
Available Sizes
Frequently Asked Questions
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