BSI-401
BSI-401 is an orally active PARP-1 inhibitor. BSI-401 alone and in synergism with Oxaliplatin (HY-17371) inhibits pancreatic cancer[1].
Product Specifications
CAS Number
[142404-10-2]
UNSPSC
12352005
Target
PARP
Related Pathways
Cell Cycle/DNA Damage; Epigenetics
Field of Research
Cancer
Smiles
O=C1C=CC2=C(I)C([N+]([O-])=O)=CC=C2O1
Molecular Formula
C9H4INO4
Molecular Weight
317.04
References & Citations
[1]Melisi D, et al. Oral poly (ADP-ribose) polymerase-1 inhibitor BSI-401 has antitumor activity and synergizes with oxaliplatin against pancreatic cancer, preventing acute neurotoxicity. Clin Cancer Res. 2009 Oct 15;15 (20) :6367-77.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Isoform
PARP1
Curated Selection
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