NDC 1308

NDC 1308 is an estradiol analogue. NDC 1308 can bind estrogen receptor beta and inhibit cancer cell proliferation by blocking chromosome replication. NDC 1308 can be used for the research of cancer, such as breast cancer[1].

Product Specifications

CAS Number

[1227511-09-2]

UNSPSC

12352005

Target

DNA/RNA Synthesis; Estrogen Receptor/ERR

Related Pathways

Cell Cycle/DNA Damage; Vitamin D Related/Nuclear Receptor

Field of Research

Cancer

Smiles

C[C@@]12[C@](CC[C@@H]2O)([H])[C@@]3([H])[C@](C4=CC=C(O)C=C4[C@H](CCCCCCOC)C3)([H])CC1

Molecular Formula

C25H38O3

Molecular Weight

386.57

References & Citations

[1]Weitman S D, et al. A steroid-based drug that binds estrogen receptor beta can inhibit cancer cell proliferation by blocking chromosome replication[J]. Cancer Research, 2010, 70 (8_Supplement) : 1721-1721.