SP187 (hydrochloride)

SP187 hydrochloride (MON-DNJ hydrochloride; UV4 hydrochloride) is an orally active, host-targeting iminosaccharide against filovirus infection. SP187 hydrochloride inhibits endoplasmic reticulum glucosidase. SP187 hydrochloride exhibits antiviral and Dengue Virus activity in vivo. SP187 hydrochloride can be used in antiviral and dengue research[1].

Product Specifications

CAS Number

[1333144-07-2]

Product Name Alternative

MON-DNJ (hydrochloride) ; UV4 (hydrochloride)

UNSPSC

12352005

Target

Dengue Virus; Influenza Virus

Related Pathways

Anti-infection

Applications

COVID-19-anti-virus

Field of Research

Infection

Smiles

OC[C@H]1N(C[C@H](O)[C@@H](O)[C@@H]1O)CCCCCCCCCOC.Cl

Molecular Formula

C16H34ClNO5

Molecular Weight

355.90

References & Citations

[1]Warfield KL, et al. Inhibition of endoplasmic reticulum glucosidases is required for in vitro and in vivo dengue antiviral activity by the iminosugar UV-4. Antiviral Res. 2016 May;129:93-98.