Aftobetin

Aftobetin is a non-invasive molecular probe used for the early diagnosis of Alzheimer's disease (AD) . Aftobetin can specifically bind to the aggregated β-amyloid peptide (Aβ) in the lens of the eye, enabling the early diagnosis of AD through a rapid and painless detection method[1].

Product Specifications

CAS Number

[1208971-05-4]

UNSPSC

12352100

Target

Amyloid-β

Related Pathways

Neuronal Signaling

Applications

Neuroscience-Neurodegeneration

Field of Research

Neurological Disease

Smiles

COCCOCCOCCOC(/C(C#N)=C/C1=CC2=C(C=C1)C=C(N3CCCCC3)C=C2)=O

Molecular Formula

C26H32N2O5

Molecular Weight

452.54

References & Citations

[1]Li Y, et al. Green Synthesis of Alzheimer's Disease Probes Aftobetin and Analogues Enabled by Flow Technology and Heterogeneous Photocatalysis. ChemSusChem. 2025 Jan 2;18 (1) :e202401214.