Aminooxyacetic acid (hemihydrochloride) (Standard)
Aminooxyacetic acid (hemihydrochloride) (Standard) is the analytical standard of Aminooxyacetic acid (hemihydrochloride) . This product is intended for research and analytical applications. Aminooxyacetic acid (Carboxymethoxylamine) hemihydrochloride is a malate-aspartate shuttle (MAS) inhibitor which also inhibits the GABA degradating enzyme GABA-T.
Product Specifications
CAS Number
2921-14-4
UNSPSC
12352100
Target
GABA Receptor; Reference Standards
Related Pathways
Membrane Transporter/Ion Channel; Neuronal Signaling; Others
Field of Research
Cancer
Smiles
OC(CON)=O.[H]Cl.[1/2]
Molecular Formula
C2H5NO3.1/2HCl
Molecular Weight
109.30
References & Citations
[1]Wang C, et al. Malate-aspartate shuttle inhibitor aminooxyacetic acid leads to decreased intracellular ATP levels and altered cell cycle of C6 glioma cells by inhibiting glycolysis. Cancer Lett. 2016 Aug 1;378 (1) :1-7.|[2]Pagliusi SR, et al. Aminooxyacetic acid induced accumulation of GABA in the rat brain. Interaction with GABA receptors and distribution in compartments. Naunyn Schmiedebergs Arch Pharmacol. 1983 Apr;322 (3) :210-5.|[3]Korangath P, et al. Targeting Glutamine Metabolism in Breast Cancer with Aminooxyacetate. Clin Cancer Res. 2015 Jul 15;21 (14) :3263-73.
Shipping Conditions
Room temperature
Scientific Category
Reference Standards
Available Sizes
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