Ritanserin (Standard)

Ritanserin (Standard) is the analytical standard of Ritanserin. This product is intended for research and analytical applications. Ritanserin (R 55667) is a highly potent, relatively selective, orally active, long acting antagonist of 5-HT2 receptor, with an IC50 of 0.9 nM, less active on Histamine H1, Dopamine D2, Adrenergic α1, Adrenergic α2 receptors[1].

Product Specifications

CAS Number

[87051-43-2]

UNSPSC

12352100

Target

5-HT Receptor; Adrenergic Receptor; Dopamine Receptor; Histamine Receptor; Reference Standards

Related Pathways

GPCR/G Protein; Immunology/Inflammation; Neuronal Signaling; Others

Field of Research

Neurological Disease

Smiles

CC1=C(C(N(C=CS2)C2=N1)=O)CCN(CC/3)CCC3=C(C4=CC=C(F)C=C4)\C5=CC=C(F)C=C5

Molecular Formula

C27H25F2N3OS

Molecular Weight

477.57

References & Citations

[1]Leysen JE, et al. Receptor-binding properties in vitro and in vivo of ritanserin: A very potent and long acting serotonin-S2 antagonist. Mol Pharmacol. 1985 Jun;27 (6) :600-11.