BMS-269223
BMS-269223 is a potent, selective and orally active factor Xa inhibitor (Ki = 6.5 nM, EC2xPT = 32 μM) . BMS-269223 can prolong prothrombin time and inhibit thrombosis formation. BMS-269223 can be used for the research of cardiovascular disease[1].
Product Specifications
CAS Number
288077-60-1
UNSPSC
12352005
Target
Factor Xa
Related Pathways
Metabolic Enzyme/Protease
Field of Research
Cardiovascular Disease
Smiles
CC(O1)=CC2=C1C=CC(N/C(N[C@H]3CCCCN(CC(N4CCCC4)=O)C3=O)=N/C#N)=C2
Molecular Formula
C23H28N6O3
Molecular Weight
436.51
References & Citations
[1]Shi Y, et al. Cyanoguanidine-based lactam derivatives as a novel class of orally bioavailable factor Xa inhibitors. Bioorg Med Chem Lett. 2009 Aug 1;19 (15) :4034-41.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
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