UBP 1112
UBP 1112 is a selective group III mGluR antagonist, with a Kd of 5.1 μM.UBP 1112 shows 96-fold affinity for group III over group II mGlu receptor (Kd, 488 μM), and shows no significant activity at group I mGlu receptor or iGlu receptor[1].
Product Specifications
CAS Number
339526-74-8
UNSPSC
12352005
Target
MGluR
Related Pathways
GPCR/G Protein; Neuronal Signaling
Field of Research
Neurological Disease
Solubility
10 mM in DMSO
Smiles
OC(C(N)(C1=CC(C)=C(P(O)(O)=O)C=C1)C)=O
Molecular Formula
C10H14NO5P
Molecular Weight
259.20
References & Citations
[1]Miller JC, et al. Phenylglycine derivatives as antagonists of group III metabotropic glutamate receptors expressed on neonatal rat primary afferent terminals. Br J Pharmacol. 2003 Aug;139 (8) :1523-31.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Frequently Asked Questions
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