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PF-03671148

PF-03671148 is an ALK5 inhibitor. PF-03671148 can reduce TGFβ induced fibrotic gene expression in fibroblasts. PF-03671148 has potential utility for the prevention of dermal scarring[1].

Product Specifications

CAS Number

1378524-25-4

UNSPSC

12352005

Target

Anaplastic lymphoma kinase (ALK)

Related Pathways

Protein Tyrosine Kinase/RTK

Field of Research

Others

Smiles

O=C1C2=C(N=CN1C)C=CC(C3=CC=NN3C4=CC=CC(C)=N4)=C2

Molecular Formula

C18H15N5O

Molecular Weight

317.34

References & Citations

[1]Boys ML, et al. Discovery of a series of 2- (1H-pyrazol-1-yl) pyridines as ALK5 inhibitors with potential utility in the prevention of dermal scarring. Bioorg Med Chem Lett. 2012 May 15;22 (10) :3392-7.

Shipping Conditions

Room temperature

Scientific Category

Reference compound1

Clinical Information

No Development Reported

Frequently Asked Questions

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