PF-03671148
PF-03671148 is an ALK5 inhibitor. PF-03671148 can reduce TGFβ induced fibrotic gene expression in fibroblasts. PF-03671148 has potential utility for the prevention of dermal scarring[1].
Product Specifications
CAS Number
[1378524-25-4]
UNSPSC
12352005
Target
Anaplastic lymphoma kinase (ALK)
Related Pathways
Protein Tyrosine Kinase/RTK
Field of Research
Others
Smiles
O=C1C2=C(N=CN1C)C=CC(C3=CC=NN3C4=CC=CC(C)=N4)=C2
Molecular Formula
C18H15N5O
Molecular Weight
317.34
References & Citations
[1]Boys ML, et al. Discovery of a series of 2- (1H-pyrazol-1-yl) pyridines as ALK5 inhibitors with potential utility in the prevention of dermal scarring. Bioorg Med Chem Lett. 2012 May 15;22 (10) :3392-7.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Curated Selection
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