Tetrahydrobiopterin
Tetrahydrobiopterin ((Rac) -Sapropterin) is a cofactor of the aromatic amino acid hydroxylases enzymes and also acts as an essential cofactor for all nitric oxide synthase (NOS) isoforms.
Product Specifications
CAS Number
[17528-72-2]
Product Name Alternative
(Rac) -Sapropterin
UNSPSC
12352005
Hazard Statement
H302, H315, H319, H335
Target
Endogenous Metabolite; NO Synthase
Related Pathways
Immunology/Inflammation; Metabolic Enzyme/Protease
Applications
COVID-19-immunoregulation
Field of Research
Inflammation/Immunology
Concentration
10mM
Purity
99.72
Solubility
DMSO : 50 mg/mL (ultrasonic)
Smiles
O=C1C2=C(NC(N)=N1)NCC(C(O)C(O)C)N2
Molecular Formula
C9H15N5O3
Molecular Weight
241.25
Precautions
H302, H315, H319, H335
References & Citations
[1]Rivera JC, et al. Tetrahydrobiopterin (BH4) deficiency is associated with augmented inflammation and microvascular degeneration in the retina. J Neuroinflammation. 2017 Sep 6;14 (1) :181.
Shipping Conditions
Blue Ice
Storage Conditions
-20°C (Powder, protect from light, stored under nitrogen)
Scientific Category
Natural Products
Clinical Information
Launched
Isoform
Human Endogenous Metabolite
Available Sizes
Curated Selection
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