Denotivir
Denotivir (Vratizolin) is an orally active antiviral agent for herpes simplex virus (HSV) and varicella-zoster virus (VZV) . Denotivir inhibits the proliferation of various cancer cells, and exhibits anti-leukemic activity. Denotivir inhibits the generation of TNF-α, IL-1 and IL-6, exhibits immunosuppressive efficacy[1].
Product Specifications
CAS Number
51287-57-1
Product Name Alternative
Vratizolin; Wratizolin
UNSPSC
12352005
Target
HSV; Interleukin Related
Related Pathways
Anti-infection; Immunology/Inflammation
Field of Research
Cancer; Infection; Inflammation/Immunology
Smiles
ClC(C=C1)=CC=C1NC(C2=C(SN=C2C)NC(C3=CC=CC=C3)=O)=O
Molecular Formula
C18H14ClN3O2S
Molecular Weight
371.84
References & Citations
[1]Machoń Z, et al., Immunotropic activity of vratizolin (ITCL, Denotivir) . Pol J Pharmacol. 2001 Jul-Aug;53 (4) :377-83.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Frequently Asked Questions
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