DX-9065a (free base)
DX-9065a free base is a selective, nonpeptidic, and orally active factor Xa (FXa) inhibitor with a Ki of 41 nM for human FXa. DX-9065a free base has low activity against other serine proteases. DX-9065a free base has strong anticoagulant actions[1][2].
Product Specifications
CAS Number
150612-55-8
UNSPSC
12352005
Target
Factor Xa
Related Pathways
Metabolic Enzyme/Protease
Applications
Neuroscience-Neuromodulation
Field of Research
Cardiovascular Disease
Smiles
N=C(N)C1=CC=C2C(C=C(C[C@H](C(O)=O)C3=CC=C(O[C@@H]4CN(C(C)=N)CC4)C=C3)C=C2)=C1
Molecular Formula
C26H28N4O3
Molecular Weight
444.53
References & Citations
[1]Brigitte Kaiser. DX-9065a, a direct inhibitor of factor Xa. Cardiovasc Drug Rev. 2003 Summer;21 (2) :91-104.|[2]J M Herbert, et al. DX 9065A a novel, synthetic, selective and orally active inhibitor of factor Xa: in vitro and in vivo studies. J Pharmacol Exp Ther. 1996 Mar;276 (3) :1030-8.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Frequently Asked Questions
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