Polyinosinic-polycytidylic acid (GMP Like)
Polyinosinic-polycytidylic acid (Poly (I:C) ) (GMP Like) is the GMP Like class Polyinosinic-polycytidylic acid , and can be used as pharmaceutical excipients. Polyinosinic-polycytidylic acid (Poly (I:C) ) is a synthetic analog of double-stranded RNA and an agonist of toll-like receptor 3 (TLR3) and retinoic acid inducible gene I (RIG-I) -like receptors (RIG-I and MDA5). Polyinosinic-polycytidylic acid can be used as a vaccine adjuvant to enhance innate and adaptive immune responses, and to alter the tumor microenvironment. Polyinosinic-polycytidylic acid can directly trigger cancer cells to undergo apoptosis[1][2].
Product Specifications
CAS Number
24939-03-5
Product Name Alternative
Poly (I:C) (GMP Like)
UNSPSC
12352005
Hazard Statement
H302, H315, H319, H412
Target
Apoptosis; Bcl-2 Family; HSP; Interleukin Related; PKD; Toll-like Receptor (TLR)
Related Pathways
Apoptosis; Cell Cycle/DNA Damage; Immunology/Inflammation; Metabolic Enzyme/Protease
Applications
COVID-19-anti-virus
Field of Research
Cancer; Infection; Inflammation/Immunology
Smiles
O[C@H]1[C@@H](O[C@H](COP(O)(O)=O)[C@H]1O)N2C3=C(C(NC=N3)=O)N=C2.O[C@H]4[C@H](N5C(N=C(N)C=C5)=O)O[C@H](COP(O)(O)=O)[C@H]4O.[x].[x]
Molecular Formula
(C10H13N4O8P) x. (C9H14N3O8P) x
Precautions
H302, H315, H319, H412
References & Citations
Shipping Conditions
Room Temperature
Storage Conditions
4°C, sealed storage, away from moisture and light
Scientific Category
GMP Small Molecules
Clinical Information
No Development Reported
Available Sizes
Frequently Asked Questions
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