8-Prenylchrysin

8-prenylchrysin is a C8-prenylated flavonoid. 8-prenylchrysin inhibits P-gp. 8-prenylchrysin can be used for tumor research[1].

Product Specifications

CAS Number

[34125-75-2]

UNSPSC

12352005

Target

P-glycoprotein

Related Pathways

Membrane Transporter/Ion Channel

Field of Research

Cancer

Smiles

O=C1C2=C(O)C=C(O)C(C/C=C(C)\C)=C2OC(C3=CC=CC=C3)=C1

Molecular Formula

C20H18O4

Molecular Weight

322.35

References & Citations

[1]de Wet H, et al. Sequence requirements of the ATP-binding site within the C-terminal nucleotide-binding domain of mouse P-glycoprotein: structure-activity relationships for flavonoid binding. Biochemistry. 2001 Aug 28;40 (34) :10382-91.|[2]Wätjen W, et al. Prenylation enhances cytotoxicity of apigenin and liquiritigenin in rat H4IIE hepatoma and C6 glioma cells. Food Chem Toxicol. 2007 Jan;45 (1) :119-24.