(E) -Hyzetimibe
(E) -Hyzetimibe ((E) -HS-25) (Compound I-1Z) is the trans isomer of Hyzetimibe (HY-107176A), a cholesterol-lowering agent. (E) -Hyzetimibe has cholesterol acyltransferase (ACTA) inhibitory activity, but its cholesterol-lowering effect is relatively weak. (E) -Hyzetimibe can inhibit the entry of hepatitis C virus (HCV) into host cells, and it has a synergistic effect when used in combination with interferon-α. (E) -Hyzetimibe can be used for the study of HCV infection[1][2].
Product Specifications
CAS Number
[1266548-75-7]
Product Name Alternative
(E) -HS-25
UNSPSC
12352005
Target
Acyltransferase; Drug Isomer; HCV
Related Pathways
Anti-infection; Metabolic Enzyme/Protease; Others
Applications
Metabolism-protein/nucleotide metabolism
Field of Research
Infection; Metabolic Disease
Smiles
OC/C(C1=CC=C(C=C1)F)=C/C[C@@H]2[C@@H](C3=CC=C(C=C3)O)N(C4=CC=C(C=C4)F)C2=O
Molecular Formula
C25H21F2NO3
Molecular Weight
421.44
References & Citations
Shipping Conditions
Room temperature
Product MSDS
http://file.medchemexpress.com/batch_PDF/HY-107176/
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Explore Other Products
Discover premium biology products from our extensive collection of 20M+ items
