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Amidox

Amidox is a ribonucleotide reductase inhibitor. Amidox potentiates the action of Arabinofuranosylcytosine in leukemia[1].

Product Specifications

CAS Number

[95933-72-5]

UNSPSC

12352005

Hazard Statement

H302, H312, H332

Target

DNA/RNA Synthesis

Related Pathways

Cell Cycle/DNA Damage

Field of Research

Cancer

Purity

98.52

Smiles

N=C(NO)C1=CC=C(O)C(O)=C1

Molecular Formula

C7H8N2O3

Molecular Weight

168.15

Precautions

H302, H312, H332

References & Citations

[1]Bauer W, et al. Amidox, an inhibitor of ribonucleotide reductase, potentiates the action of Ara-C in HL-60 human promyelocytic leukemia cells. Nucleosides Nucleotides Nucleic Acids. 2004 Oct;23 (8-9) :1541-4.

Shipping Conditions

Room Temperature

Storage Conditions

4°C (Powder, protect from light, stored under nitrogen)

Scientific Category

Reference compound1

Clinical Information

No Development Reported

Available Sizes

Curated Selection

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