CLT-28643
CLT-28643 is an integrin α5β1 inhibitor. CLT-28643 can inhibit the high expression of integrin α5β1 in the bleb at early time-points after surgery and promote wound healing process[1].
Product Specifications
CAS Number
[1153631-91-4]
UNSPSC
12352005
Target
Integrin
Related Pathways
Cytoskeleton
Field of Research
Others
Smiles
CNC(C1=CC(C(NC2=CC=C(OC)C=C2)=C(C(O)=O)C=N3)=C3C=C1)=O
Molecular Formula
C19H17N3O4
Molecular Weight
351.36
References & Citations
[1]Van Bergen T, et al. Integrin α5β1 Inhibition by CLT-28643 Reduces Postoperative Wound Healing in a Mouse Model of Glaucoma Filtration Surgery. Invest Ophthalmol Vis Sci. 2016 Nov 1;57 (14) :6428-6439.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Isoform
α5β1
Curated Selection
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