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MK-5932

MK-5932 is an orally active, selective, dissociated partial glucocorticoid receptor agonist. MK-5932 inhibits IL-6. MK-5932 induces lymphopenia. MK-5932 restores glucose levels to normal. MK-5932 shows anti-inflammatory effects[1].

Product Specifications

CAS Number

[1021539-02-5]

UNSPSC

12352005

Target

Glucocorticoid Receptor

Related Pathways

Immunology/Inflammation; Vitamin D Related/Nuclear Receptor

Field of Research

Metabolic Disease; Inflammation/Immunology

Smiles

C[C@]12CC3=C(C=C1CC[C@@]2(O)CCC4=CC=C(F)C=C4C(N)=O)N(C5=CC=C(F)C=C5)N=C3

Molecular Formula

C26H25F2N3O2

Molecular Weight

449.49

References & Citations

[1]Brandish PE, et al. The preclinical efficacy, selectivity and pharmacologic profile of MK-5932, an insulin-sparing selective glucocorticoid receptor modulator. Eur J Pharmacol. 2014 Feb 5;724:102-11.

Shipping Conditions

Room temperature

Product MSDS

http://file.medchemexpress.com/batch_PDF/HY-107122/

Scientific Category

Reference compound1

Clinical Information

No Development Reported

Curated Selection

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