ALX-5407
ALX-5407 ((R) -NFPS) is a selective and orally active glycine transporter GlyT1 inhibitor with an IC50 value of 3 nM. ALX-5407 can be used the research of N-methyl-D-aspartate-receptor function and schizophrenia[1].
Product Specifications
CAS Number
571147-18-7
Product Name Alternative
(R) -NFPS
UNSPSC
12352005
Target
GlyT
Related Pathways
Membrane Transporter/Ion Channel; Neuronal Signaling
Field of Research
Neurological Disease
Smiles
OC(CN(C)CC[C@H](C1=CC=C(C=C1)F)OC2=CC=C(C3=CC=CC=C3)C=C2)=O
Molecular Formula
C24H24FNO3
Molecular Weight
393.45
References & Citations
[1]Atkinson BN, et al. ALX 5407: a potent, selective inhibitor of the hGlyT1 glycine transporter. Mol Pharmacol. 2001 Dec;60 (6) :1414-20.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
Phase 1
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