ALX-5407

ALX-5407 ((R) -NFPS) is a selective and orally active glycine transporter GlyT1 inhibitor with an IC50 value of 3 nM. ALX-5407 can be used the research of N-methyl-D-aspartate-receptor function and schizophrenia[1].

Product Specifications

CAS Number

[571147-18-7]

Product Name Alternative

(R) -NFPS

UNSPSC

12352005

Target

GlyT

Related Pathways

Membrane Transporter/Ion Channel; Neuronal Signaling

Field of Research

Neurological Disease

Smiles

OC(CN(C)CC[C@H](C1=CC=C(C=C1)F)OC2=CC=C(C3=CC=CC=C3)C=C2)=O

Molecular Formula

C24H24FNO3

Molecular Weight

393.45

References & Citations

[1]Atkinson BN, et al. ALX 5407: a potent, selective inhibitor of the hGlyT1 glycine transporter. Mol Pharmacol. 2001 Dec;60 (6) :1414-20.

Shipping Conditions

Room temperature

Scientific Category

Reference compound1

Clinical Information

Phase 1

Curated Selection

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