WCK-1152
WCK-1152 is a fluoroquinolone antibacterial agent. WCK-1152 is active against resistant pathogens bearing mutations of DNA gyrase and/or topoisomerase IV which also express efflux pumps. WCK-1152 can be used for the research of infection, such as respiratory infections caused by resistant pneumococci and staphylococci[1].
Product Specifications
CAS Number
[1332393-03-9]
UNSPSC
12352005
Target
Bacterial
Related Pathways
Anti-infection
Applications
COVID-19-immunoregulation
Field of Research
Infection
Smiles
COC1=C2N(C3CC3)C=C(C(C2=CC(F)=C1N4CC(C)([C@H](CC4)N)C)=O)C(O)=O.Cl.O
Molecular Formula
C21H29ClFN3O5
Molecular Weight
457.92
References & Citations
[1]Bhawsar S, et al. WCK 1152, WCK 1153: Discovery and structure activity relationship for the treatment of resistant pneumococcal and staphylococcal respiratory infections. Bioorg Med Chem Lett. 2022 May 1;63:128665.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
Phase 1
Curated Selection
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