BC-1175
BC-1175 (CB-181963) is a novel cephalosporin and antibacterial agent. CB-181963 displays strong binding to altered PBP 2a. CB-181963 demonstrates marked efficacy against MRSA, Klebsiella pneumoniae, Streptococcus pneumoniae, and Escherichia coli[1][2].
Product Specifications
CAS Number
635292-67-0
Product Name Alternative
CB-181963
UNSPSC
12352005
Target
Bacterial; Penicillin-binding protein (PBP)
Related Pathways
Anti-infection
Field of Research
Infection
Smiles
OC(C1=C(/C=N/N(C)C(N2CCNCC2)=N)CS[C@@]([C@@H]3NC(/C(C4=NSC(N)=N4)=N\OCF)=O)([H])N1C3=O)=O
Molecular Formula
C19H24FN11O5S2
Molecular Weight
569.59
References & Citations
[1]Miller K, et al. Antistaphylococcal activity of the novel cephalosporin CB-181963 (CAB-175) . J Antimicrob Chemother. 2005 Apr;55 (4) :579-82.|[2]Huang V, et al. In vitro activities of a novel cephalosporin, CB-181963 (CAB-175), against methicillin-susceptible or -resistant Staphylococcus aureus and glycopeptide-intermediate susceptible staphylococci. Antimicrob Agents Chemother. 2004 Jul;48 (7) :2719-23.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
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