Nitrefazole (Standard)

Nitrefazole (Standard) is the analytical standard of Nitrefazole. This product is intended for research and analytical applications. Nitrefazole is a 4-nitroimidazole derivative with strong and long lasting inhibition of aldehyde dehydrogenase (ALDH), an enzyme involved in the metabolism of alcohol.

Product Specifications

CAS Number

[21721-92-6]

UNSPSC

12352100

Target

Aldehyde Dehydrogenase (ALDH) ; Reference Standards

Related Pathways

Metabolic Enzyme/Protease; Others

Field of Research

Metabolic Disease

Smiles

CC1=NC([N+]([O-])=O)=CN1C2=CC=C([N+]([O-])=O)C=C2

Molecular Formula

C10H8N4O4

Molecular Weight

248.19

References & Citations

[1]Koda LY, Madamba SG, Bloom FE. Hypotensive response of ethanol in rats pretreated with disulfiram or nitrefazole. Life Sci. 1984;35 (16) :1659-1665. |[2]Zorzano A, Herrera E. Differences in the kinetic properties and sensitivity to inhibitors of human placental, erythrocyte, and major hepatic aldehyde dehydrogenase isoenzymes. Biochem Pharmacol. 1990;39 (5) :873-878.