Nitrefazole (Standard)
Nitrefazole (Standard) is the analytical standard of Nitrefazole. This product is intended for research and analytical applications. Nitrefazole is a 4-nitroimidazole derivative with strong and long lasting inhibition of aldehyde dehydrogenase (ALDH), an enzyme involved in the metabolism of alcohol.
Product Specifications
CAS Number
21721-92-6
UNSPSC
12352100
Target
Aldehyde Dehydrogenase (ALDH) ; Reference Standards
Related Pathways
Metabolic Enzyme/Protease; Others
Field of Research
Metabolic Disease
Smiles
CC1=NC([N+]([O-])=O)=CN1C2=CC=C([N+]([O-])=O)C=C2
Molecular Formula
C10H8N4O4
Molecular Weight
248.19
References & Citations
[1]Koda LY, Madamba SG, Bloom FE. Hypotensive response of ethanol in rats pretreated with disulfiram or nitrefazole. Life Sci. 1984;35 (16) :1659-1665. |[2]Zorzano A, Herrera E. Differences in the kinetic properties and sensitivity to inhibitors of human placental, erythrocyte, and major hepatic aldehyde dehydrogenase isoenzymes. Biochem Pharmacol. 1990;39 (5) :873-878.
Shipping Conditions
Room temperature
Scientific Category
Reference Standards
Frequently Asked Questions
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