Surinabant

Surinabant (SR 147778) is an orally active, selective cannabinoid receptor type 1 CB1R antagonist. Surinabant is used in studies of obesity and alcoholism[1][2].

Product Specifications

CAS Number

[288104-79-0]

Product Name Alternative

SR 147778

UNSPSC

12352005

Target

Cannabinoid Receptor

Related Pathways

GPCR/G Protein; Neuronal Signaling

Field of Research

Metabolic Disease

Smiles

CCC1=C(C2=CC=C(Br)C=C2)N(C3=C(C=C(Cl)C=C3)Cl)N=C1C(NN4CCCCC4)=O

Molecular Formula

C23H23BrCl2N4O

Molecular Weight

522.26

References & Citations

[1] Klumpers LE, et al. Surinabant, a selective cannabinoid receptor type 1 antagonist, inhibits Δ9-tetrahydrocannabinol-induced central nervous system and heart rate effects in humans. Br J Clin Pharmacol. 2013 Jul;76 (1) :65-77.|[2]Fischler PV, et al. Off-label and investigational drugs in the treatment of alcohol use disorder: A critical review. Front Pharmacol. 2022 Oct 3;13:927703.