Lergotrile
Lergotrile is a potent and orally active dopamine agonist and a prolactin secretion inhibitor. Lergotrile inhibits prolactin release from pituitaries by activating an adenohypophyseal dopamine receptor. Lergotrile has the potential for the research of Parkinson's disease[1][2][3].
Product Specifications
CAS Number
36945-03-6
UNSPSC
12352005
Target
Dopamine Receptor
Related Pathways
GPCR/G Protein; Neuronal Signaling
Field of Research
Endocrinology; Neurological Disease
Smiles
ClC1=C2C3=C(N1)C=CC=C3[C@]4([H])[C@@](N(C[C@@H](C4)CC#N)C)([H])C2
Molecular Formula
C17H18ClN3
Molecular Weight
299.80
References & Citations
[1]Clemens JA, et al. Inhibition of prolactin secretion by lergotrile mesylate: mechanism of action. Acta Endocrinol (Copenh) . 1975 Jun;79 (2) :230-7. |[2]Lemberger L, et al. The inhibitory effect of an ergoline derivative (lergotrile, compound 83636) on prolactin secretion in man. J Clin Endocrinol Metab. 1974 Sep;39 (3) :579-84. |[3]Lieberman A, et al. Treatment of Parkinson's disease with lergotrile mesylate. JAMA. 1977 Nov 28;238 (22) :2380-2.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Frequently Asked Questions
More Discoveries
Explore Other Products
Browse additional items from our catalog
bs-10362R-BF555-01 20 µL
TPOR Polyclonal Antibody, AbBy Fluor™ 555 Conjugated
Sign In for Pricing
View Details bs-10362R-BF555-02 100 µL
TPOR Polyclonal Antibody, AbBy Fluor™ 555 Conjugated
Sign In for Pricing
View Details ![Rabbit Polyclonal FAM120B Antibody [DyLight 650]](https://cdn.genprice.uk/genprice/uk/genprice5.webp)
NBP1-76315C 0.1 mL
Rabbit Polyclonal FAM120B Antibody [DyLight 650]
Sign In for Pricing
View Details