Corthrombin

Corthrombin (CVS 995) is a potent alpha-keto-amide thrombin inhibitor with Ki of 1 pM. Corthrombin can be used for the research of cardiovascular disease[1].

Product Specifications

CAS Number

[166247-65-0]

Product Name Alternative

CVS 995

UNSPSC

12352005

Target

Thrombin

Related Pathways

Metabolic Enzyme/Protease

Field of Research

Cardiovascular Disease

Smiles

CCCC(CCC)C(NC(CC(O)=O)C(N1C(CCC1)C(NC(CCCNC(N)=N)C(C(NCC(NCC(NCC(NCC(NCC(NC(CC(N)=O)C(NCC(NC(CC(O)=O)C(NC(C(NC(CCC(O)=O)C(NC(CCC(O)=O)C(NC(C(C)CC)C(N2C(CCC2)C(NC(CCC(O)=O)C(NC(C(NC(C(O)=O)CC(C)C)=O)CC3=CC=C(O)C=C3)=O)=O)=O)=O)=O)=O)CC4=CC=CC=C4)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O

Molecular Formula

C94H137N23O34

Molecular Weight

2133.23

References & Citations

[1]Krishnan R, et al. Synthesis, structure, and structure-activity relationships of divalent thrombin inhibitors containing an alpha-keto-amide transition-state mimetic. Protein Sci. 1996 Mar;5 (3) :422-33.