Pimilprost

Pimilprost (SM 10902) is a prostaglandin I1 analogue. Pimilprost exhibits antithrombotic and increases cAMP levels. Pimilprost can promote wound healing through the stimulation of angiogenesis and the improvement of blood flow in diabetic mice. Pimilprost can be used for the research of metabolic and cardiovascular disease, such as diabetes[1][2].

Product Specifications

CAS Number

[139403-31-9]

Product Name Alternative

SM 10902

UNSPSC

12352211

Target

Prostaglandin Receptor

Related Pathways

GPCR/G Protein

Field of Research

Metabolic Disease; Cardiovascular Disease

Smiles

CCCC[C@H](C)C[C@H](O)/C=C/[C@@H]1[C@]2([H])[C@](C[C@@H](CCOCC(OC)=O)C2)([H])C[C@H]1O

Molecular Formula

C23H40O5

Molecular Weight

396.56

References & Citations

[1]Nishimura T, et al. Antithrombotic effect of topically applied 3-oxa-methano-prostaglandin I1 in the microcirculation and antiplatelet functions of its active form. Prostaglandins. 1996 Feb;51 (2) :149-59.|[2]Yamamoto T, et al. Effect of topical application of a stable prostacyclin analogue, SM-10902 on wound healing in diabetic mice. Eur J Pharmacol. 1996 Apr 29;302 (1-3) :53-60.