Domitroban

Domitroban is a thromboxane A2 receptor (TBXA2R) antagonist. Domitroban can inhibit platelet aggregation. Domitroban can be used for the research of cardiovascular disease, such as thrombosis[1].

Product Specifications

CAS Number

[112966-96-8]

UNSPSC

12352005

Target

Prostaglandin Receptor

Related Pathways

GPCR/G Protein

Field of Research

Cardiovascular Disease

Smiles

O=S(N[C@@H]1[C@H]([C@H]2C[C@@H]1CC2)C/C=C\CCCC(O)=O)(C3=CC=CC=C3)=O

Molecular Formula

C20H27NO4S

Molecular Weight

377.50

References & Citations

[1]Fujimura A, et al. Effect of treatment at night with S-1452, a thromboxane A2 receptor antagonist, on the morning rise in platelet aggregation. Eur J Clin Pharmacol. 1992;43 (5) :501-5.