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NIP-121

NIP-121 is a new type of potassium channel opener. NIP-121 significantly reduces mean pulmonary artery pressure and total pulmonary resistance through vasodilation. NIP-121 can be used for research on pulmonary arterial hypertension[1].

Product Specifications

CAS Number

[135244-62-1]

UNSPSC

12352005

Target

Potassium Channel

Related Pathways

Membrane Transporter/Ion Channel

Field of Research

Cardiovascular Disease

Smiles

O[C@@H]1[C@@H](N2C(CCCC2)=O)C3=CC4=NON=C4C=C3OC1(C)C

Molecular Formula

C16H19N3O4

Molecular Weight

317.34

References & Citations

[1] Tanaka H, et al. Cardioprotective effects of NIP-121, a novel ATP-sensitive potassium channel opener, during ischemia and reperfusion in coronary perfused guinea pig myocardium. J Cardiovasc Pharmacol. 1996 May;27 (5) :695-701.

Shipping Conditions

Room temperature

Scientific Category

Reference compound1

Clinical Information

No Development Reported

Curated Selection

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