NIP-121
NIP-121 is a new type of potassium channel opener. NIP-121 significantly reduces mean pulmonary artery pressure and total pulmonary resistance through vasodilation. NIP-121 can be used for research on pulmonary arterial hypertension[1].
Product Specifications
CAS Number
135244-62-1
UNSPSC
12352005
Target
Potassium Channel
Related Pathways
Membrane Transporter/Ion Channel
Field of Research
Cardiovascular Disease
Smiles
O[C@@H]1[C@@H](N2C(CCCC2)=O)C3=CC4=NON=C4C=C3OC1(C)C
Molecular Formula
C16H19N3O4
Molecular Weight
317.34
References & Citations
[1] Tanaka H, et al. Cardioprotective effects of NIP-121, a novel ATP-sensitive potassium channel opener, during ischemia and reperfusion in coronary perfused guinea pig myocardium. J Cardiovasc Pharmacol. 1996 May;27 (5) :695-701.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
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