Nileprost

Nileprost is a prostacyclin analogue. Nileprost is a mixed type PGI2/PGE2 agonist. Nileprost can be studied in research on acute myocardial ischemia[1][2].

Product Specifications

CAS Number

[71097-83-1]

UNSPSC

12352005

Target

Prostaglandin Receptor

Related Pathways

GPCR/G Protein

Applications

Neuroscience-Neuromodulation

Field of Research

Cardiovascular Disease

Smiles

CCCCC(C)[C@H](O)/C=C/[C@@H]1[C@]2([H])[C@@](C[C@H]1O)([H])O/C(C2)=C(C#N)\CCCC(O)=O

Molecular Formula

C22H33NO5

Molecular Weight

391.50

References & Citations

[1]Yoneda, M., & Ohkawa, Y. (1990) . Degradation and isomerization of nileprost, 5-cyano-16-methyl-prostacyclin, in aqueous solution. Chemical & pharmaceutical bulletin, 38 (9), 2507-2512. |[2]Darius, H., et al., (1987) . Cardiovascular actions in vitro and cardioprotective effects in vivo of nileprost, a mixed type PGI2/PGE2 agonist. Journal of cardiovascular pharmacology, 10 (2), 144-152.